Rolip 20 | View Uses, Dosage, Interaction, Contraindication, Price | ePharma
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Rolip 20mg Tablet 10pcs

Generic: Rosuvastatin

Type: Tablet

Pack Size: 10 Pcs

Rosuvastatin

  • It is used in the treatment of high cholesterol levels and to correct abnormal cholesterol.
  • To slow down the progression of atherosclerosis, a condition of narrowing of blood vessels due to fat build-up.
  • It is also known to reduce the risk of heart-related conditions such as stroke and heart attack.

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Discount Price: ৳ 288
MRP: ৳ 300 4% Off

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✅ Description:

  • Rolip 20mg Tablet is a medicine used in the treatment of high blood cholesterol and triglycerides (fats) levels.
  • Rolip 20mg Tablet works by blocking the production of unhealthy fats in your body and prevents the risk of heart problems and stroke (a condition that causes reduced oxygen supply to the brain).
  • Rolip 20mg Tablet may be taken with or without food. Take the dose as directed by your doctor.
  • Take it regularly at the same time for the ease of remembering. Avoid taking more than the recommended dose. Your doctor may suggest tests to regularly monitor your lipid profiles (fat levels in the blood) to make sure the medicine is working properly.
  • Rolip 20mg Tablet is not recommended for use if you are allergic to it. Avoid taking this medicine if you have liver problems.
  • Use this medicine with caution if you have diabetes, hypothyroidism (low levels of thyroid hormone in the body), or kidney problems. Inform your doctor if you are taking any other medicine as they may interact with this medicine and cause undesired effects.
  • Rolip 20mg Tablet is not recommended for use in children below 6 years of age as the safety and efficacy data is not available.

Safety Advices


Alcohol
UNSAFE

Caution is advised when alcohol is consumed with this medicine. Kindly consult your doctor.


Pregnancy
CONSULT YOUR DOCTOR

Pregnant women must consult a doctor before using Rolip 20mg Tablet.


Breastfeeding

In the case of breastfeeding, you must consult the doctor.


Driving
SAFE

Rolip 20mg Tablet usually does not affect the patient's ability to drive.


Kidney
CONSULT YOUR DOCTOR

Caution must be taken in patients with kidney disease. Adjustment of dose is needed. Kindly consult your doctor before taking it.


Liver
CONSULT YOUR DOCTOR

Caution must be taken in patients with liver disease. Adjustment of dose is needed. Kindly consult your doctor before taking it.

Similar Products

✔️ Uses of Rolip 20mg Tablet
  • Hyperlipidemia
  • Hypertriglyceridemia
  • Type 3 Hyperlipoproteinemia
✔️ Side Effects of Rolip 20mg Tablet

Rolip is generally well tolerated. The most frequent adverse events related to Rolip include:

  • Headache
  • Myalgia
  • Constipation
  • Asthenia
  • Abdominal pain
  • Nausea
✔️ How does Rolip 20mg Tablet work?

Rolip 20 works by interfering with the process of cholesterol synthesis. Cholesterol is made by an enzyme HMG-CoA reductase, rosuvastatin inhibits this enzyme, thus lowering cholesterol levels. It also increases good cholesterol known as high-density lipoprotein (HDL) levels.

✔️ Quick Suggestions:
  • In general, Rolip 20mg Tablet is safe. It may cause diarrhea, gas, or an upset stomach. If any of these happen to you, take it with food.
  • Inform your doctor if you experience fatigue, muscle weakness, or muscle pain.
  • Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems such as stomach pains, unusually dark urine, or yellowing of skin or eyes.
  • Inform your doctor if you have kidney disease, liver disease, or diabetes before starting treatment with this medicine. If you are diabetic, monitor your blood sugar level regularly as Rosuvas 40 Tablet may cause an increase in your blood sugar level.
  • Do not take Rosuvas 40 Tablet if you are pregnant, planning a pregnancy, or breastfeeding.
✔️ Indication

Rolip is indicated for:

  • Heterozygous Hypercholesterolemia (Familial and Non-familial)
  • Homozygous Hypercholesterolemia (Familial)
  • Mixed Dyslipidemia (Fredrickson Type IIa and IIb)
  • Primary prevention of cardiovascular disease
✔️ Pharmacology

Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor of cholesterol. Rosuvastatin works by:

  1. Increasing the number of hepatic LDL receptors on the cell surface enhances the uptake and catabolism of LDL.
  2. Inhibiting hepatic synthesis of VLDL, which reduces the total number of VLDL and LDL particles.
✔️ Dosage & Administration
  • General Dose Range: 5-40 mg once daily. Use the 40 mg dose only for patients not reaching the LDL-C goal with 20 mg.
  • HoFH (Homozygous Familial Hypercholesterolemia): Starting dose 20 mg/day.
  • Pediatric Patients with HeFH (Heterozygous Familial Hypercholesterolemia):
    • 5-10 mg/day for patients 8 to less than 10 years of age.
    • 5-20 mg/day for patients 10 to 17 years of age.
  • Pediatric Patients with HoFH: 20 mg/day for patients 7 to 17 years of age.
  • Take as per doctor's advice.

Rosuvastatin can be taken with or without food, at any time of day.

✔️ Interaction

Significant drug interactions of Rolip include:

  • Cyclosporine: Increases Rolip exposure. Limit the Rolip dose to 5 mg once daily.
  • Gemfibrozil: Combination should be avoided. If used together, limit the Rolip dose to 10 mg once daily.
  • Lopinavir/Ritonavir or Atazanavir/Ritonavir: Increases Rolip exposure. Limit the Rolip dose to 10 mg once daily.
  • Coumarin Anticoagulants: Prolongs international normalized ratio (INR). Achieve stable INR before starting Rolip and monitor frequently until stable.
  • Concomitant Lipid-lowering Therapies: Use with fibrates and niacin products may increase the risk of skeletal muscle effects.
✔️ Contraindications

Rosuvastatin is contraindicated in patients with:

  • Known hypersensitivity to product components.
  • Liver disease, including unexplained persistent elevations in hepatic transaminase levels.
  • Pregnancy and women who may become pregnant.
  • Nursing mothers.
✔️ Pregnancy & Lactation
  • Safety in pregnant women has not been established.
  • It is not known whether Rosuvastatin is excreted in human milk.
✔️ Precaution & Warnings:
  • Skeletal Muscle Effects (e.g., myopathy and rhabdomyolysis): Risks increase with the use of 40 mg dose, advanced age (>65 years), hypothyroidism, renal impairment, and combination use with cyclosporine, lopinavir/ritonavir, atazanavir/ritonavir, or certain other lipid-lowering drugs. Patients should report unexplained muscle pain, tenderness, or weakness. Discontinue Rolip if signs or symptoms appear.
  • Liver Enzyme Abnormalities and Monitoring: Persistent elevations in hepatic transaminases can occur. Monitor liver enzymes before and during treatment.
✔️ Storage Conditions:
  • Keep below 30°C, protected from light and moisture.
  • Keep out of reach of children.
Frequently Asked Questions (FAQ)

Hyperlipidaemia refers to high levels of bad cholesterol and triglycerides (types of fats) in the blood. Rolip 20MG Tablet is used to treat hyperlipidaemia by lowering these fat levels.

High levels of fats in the blood can deposit in blood vessels, increasing the risk of heart problems. Rolip 20MG Tablet helps prevent heart attacks by reducing these fat levels and preventing their deposition in blood vessels.

Yes, strokes occur due to insufficient blood supply to the brain, often caused by narrowing blood vessels due to fat deposits. Rolip 20MG Tablet reduces cholesterol levels, helping to prevent the narrowing of blood vessels and reducing the risk of stroke.

The peak effect of this medication can be observed in 5 hours after multiple dosing.

The effect of this medicine lasts for a duration of 2 to 3 days.
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Check our pricing section for Rolip 20mg Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
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